Effect of extracorporeal membrane oxygenation in neonates with complex congenital heart disease after cardiac surgery
Yu Xindi
Yang Yinyu
Shen Jia
Zhang Mingjie
Liu Yujie
Zhang Wei
Wang Wei
Zhu Deming
Xu Zhuoming
Zhang Haibo
Abstract：Objective To summarise the clinical application of extracorporeal membrane oxygenation (ECMO) in the treatment of heart failure or cardiac arrest after neonatal cardiac surgery to provide a basis for further improvement of the success rate of ECMO. Methods Clinical data of 10 neonates who received ECMO support after cardiac surgery in our center from September 2016 to October 2017 were retrospectively analyzed. Results Ten neonates, aged from 2 to 25 days and weighed between 2.60 to 4.50 kg, with heart failure or cardiac arrest after open heart surgery were supported with ECMO. The duration for ECMO was from 11 to 456 hours. Six (60％) neonates were successfully weaned from ECMO and four (40％) survived to discharge. Among them, Six deaths happened in hospital, including three cases giving up treatment and three cases died of unsuccessful weaning from ECMO due to cardiac dysfunction. Bleeding, acute kidney injury and infection were the most common complications. Heart failure and abandoned treatment were two major causes of death. Conclusions ECMO could provide effective support for neonates with cardiac failure or cardiac arrest after surgery for congenital heart disease. Mastering timing and indications, improving the management of ECMO, emphasizing on the protection of organ function and reducing the incidence of complications are important factors to improve the survival rate.
Keywords：Extracorporeal membrane oxygenationCongenital heart diseaseCardiac failureCardiac arrest
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 7-11 )