The cerebral protection effects of different methods of flow control in antegrade cerebral perfusion
Pan Xu
Tang Chu-zhong
Sun Wen-ting
Li Han
Chi Hai-tao
Zhang Peng-yu
Abstract：Objective To summarize the cerebral protection effects of selective anterograde cerebral perfusion with different flow control methods for patients suffering from aortic dissection of Stanford type A who received total arch replacement.Methods From October 2010 to August 2015,there were 70 patients suffering from Stanford type A aortic dissection.According to different flow control methods,patients were divided into three groups.T1: 22 cases,simple flow control with cerebral perfusion flow of 5-10 ml/min/kg,T2: 24 cases,the cerebral perfusion flow was based on the left radial artery pressure ranged from 40 to 70 mmHg,T3: 24 cases,pump pressure control,the average pump pressure was maintained at 70 mmHg during cerebral perfusion.Time of consciousness after operation,mechanical ventilation time,transient neurological dysfunction rate (TND),permanent neurological dysfunction rate(PND) were compared among different groups.Results Time of consciousness after operation and mechanical ventilation time in patients received the pump pressure control anterograde cerebral perfusion were shorter,with fewer suffered from TND and PND.Conclusion In patients suffering from Stanford type A aortic dissection who received intraoperative anterograde cerebral perfusion,usage of pump pressure flow control method showed fewer interference factors and better cerebral protection effects,which was simple to deal with and worth promoting.
Keywords：Aortic dissectionAnterograde cerebral perfusionFlow controlCerebral protection
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 133-135,143 )