Clinical study on early postoperative prognosis of patients with complex aortic malformation with myocardial and cerebral perfusion strategy
Zhao Cong-cong
Liu Jin-ping
Feng Zheng-yi
Zhao Ju
Hu Jin-xiao
Cui Yong-li
Li Shou-jun
Yan Jun
Abstract：Objective To investigate and evaluate the effect of cerebral and myocardial perfusion (CMP) or only-regional cerebral perfusion (only-RCP) in pediatric underwent complicated aortic surgery.Methods From 2012 to 2014,one hundred and fifty one children with coarctation of aorta (CoA) or interrupted aortic arch combined with cardiac defects such as ventricular septal defect (VSD) or atrial septal defect (ASD) undergoing one-stage corrective surgery were included in this study.They were divided into two groups,CMP group (n=56) and only-RCP group (n=85),based upon the cardiopulmonary bypass (CPB) strategy.The surgery and CPB parameters,postoperative biochemical index,recovery situation,and postoperative complications of patients were recorded and compared between two groups.Results The bypass time,arrest time,operative time,cardiac ischemia time,the length of hospital stay and respiratory support time in CMP group were significantly shorter than those in only-RCP group.The level of biochemical index which can reflect the function of liver and kidney in CMP group was also lower than that in only-RCP group.Conclusion The modified perfusion strategy of CMP could provide better prognosis for children undergoing one-stage aortic arch surgery,and may reduce the length of hospital stay and the respiratory support time.
Keywords：Cerebral and myocardial perfusionRegional cerebral perfusionAortic arch surgeryChildren
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 13-17 )