Risk factors of transfusion in infants undergoing cardiac surgery with blood-sparing strategy
Zou Li-hua
Liu Jin-ping
Feng Zheng-yi
Zhao Ju
Cui Yong-li
Zhao Ming-xia
Li Shou-jun
Yan Jun
Yan Fu-xia
Wang Xu
Abstract：Objective To evaluate the risk factors of transfusion in infants (≤15 kg) who had cardiac surgerywithapplication of amodified blood-sparing technique. Methods 283 infants were included with a new blood-sparing method, known as non-homolo?gous blood priming technique. Infants were classified into three groups:intraoperative transfusion group ( IT group) that requiredtrans?fusion during operation,postoperative transfusion group ( PT group) and transfusion-free group ( TF group) . All infants underwent rou?tine heart surgery with cardiopulmonary bypass. Clinic data and transfusion requirements were collected during operation, at ICU, and in ward. Results Multivariate logistic regression showed that lower preoperative hematocrit, lower body weight and smaller body size could reduce the risk of intra-operative transfusion [OR=0.811, CI(0.729-0.901), P<0.001;OR=0.717, CI(0.598-0.859), P<0.001;OR=0.909, CI(0.846-0.975), P=0.008]. Priming volume was associated with the increased risk of transfusion[OR=1.006, CI(1.001-1.012), P =0.032]. Similarly, body weight could reduce the risk of post-operative transfusion. However, preoperative cy?anosis was associated with increased risk of post-operative transfusion [OR=0.833, CI(0.730-0.955), P =0.009; OR=2.597, CI (1.168-5.774), P =0.019]. Conclusion Our research identified the risk and protective factors of blood sparingin infant with body weight less than 15 kg for cardiac surgery.
Keywords：Cardiopulmonary bypassInfantsBloodless transfusion
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 146-149,160 )