The influence of extracorporeal cardiopulmonary resuscitation on survival in a-dults with cardiac arrest：a meta analysis
Yu Jie
Zhang Ai-jing
Hei Fei-long
Abstract：Objective To evaluate the influence of extracorporeal cardiopulmonary resuscitation ( ECPR) on survival in adults with cardiac arrest. Methods We searched CNKI,PubMed and other databases to collect relevant studies from inception to March 2015. Two reviewers strictlyscreened studies ,extracted data,and assesed the methodological quality.Then,meta-analysis was performed by using STATA13.0 software. Results Five relevant studies involving 1305 patientswere included in our review, 295 cases belonging to ECPR group and 1010 cases belonging to conventional cardiopulmonary resuscitation ( CCPR) group. The meta-analysis showed that the survival [RR=2.74, 95% CI (2.03,3.70), P<0.001] and neurologic status[RR=2.65, 95% CI (1.86,3.77), P<0.001] of ECPR group were better than those of CCPR groupat discharge. Fourof the 5 studies used propensity score matching to build balanced cohorts with 182 patients in both groups.The results also showed superiority of ECPR over CCPR,in survival[RR=2.53, 95% CI (1. 52,4.20), P<0.001] and neurologic status at discharge [RR=3.27,95% CI (1.74,6.15), P<0.001]. Conclusions Current evi?dence suggests that the survival and neurologic status after ECPR are superior to that after CCPRat discharge.
Keywords：Cardiopulmonary resuscitationECMOSurvival at dischargeNeurologic statusMeta
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 137-140,145 )