Clinical analysis of prolonged mechanical ventilation in infants after cardiopul-monary bypass
Yang Zheng-bing
Zhou Zhi-en
Zhang Li-bing
Zhou Chun-long
Abstract：Objective To investigate the high risk factor, and methods for prevention and treatment of prolonged mechanical ventilation( PMV) after cardiopulmonary bypass( CPB) . Methods Between January 2012 and June 2013,512 patients who underwent open heart surgery were divided into two groups based on themechanical ventilation longer than 48 hours or not ( prolonged mechanical ventilation was defined as 48 hours or more).Group Ⅰ:75 patients required prolonged mechanical ventilation. Group Ⅱ:437 patients did not require prolonged mechanical ventilation. Univariate and multivariate logistic regression analysis were used to identify the risk factors. Results The mortality rate of group Ⅰwas 10.7%(8/75).The main causes of complication were respiratory failure (45 ca?ses), low cardiac output syndrome (12 cases), stroke (2 cases) and multiple organ failure (5 cases). Multivariate logistic regression analysis identified emergency operation (OR 16.468), CPB time>150 min (OR 4.398), secondary CPB support (OR 18.653), PaO2/FiO2<300 mm Hg ( OR 4.606) , the volume of post-operative drainage per kg>18 ml ( OR 5.666) as the risk factors. Conclu?sion The patients with the risk factors need more preoperative care and post-operative care to avoid prolonged mechanical ventilation after CPB.
Keywords：InfantsCardiopulmonary bypassProlonged mechanical ventilationRisk factors
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 18-20 )