Application of blood saving strategy in low-weight adults with heart disease dur-ing extracorporeal circulation
Wang Hui-ying
Zhu Xiang-hui
Long Cun
Li Jing-wen
Abstract：Objective To evaluate the effect of decreasing the extracorporeal circulation ( ECC) priming volume for low-weight adults on reducing allogeneic blood transfusion in cardiac surgery. Methods Sixty low-weight adults (40-60 kg) were randomly divided into the following three groups: Group A (Dideco 905 oxygenator, children ECC circuit), group B (Xijian adult oxygenator, children ECC circuit) , group C ( Jostra VKMO7000 oxygenator, adult ECC circuit) . Intra and post-operative ( up to 24 hours after ICU adminis-tration) transfusion were collected. Rewarming time, priming volume and extubation time were also recorded. The blood gas analysis was performed at the following time points:before ECC ( T0) , after X-clamp ( T1) , rewarming ( T2) , conclusion of ECC ( T3) , arriving at ICU ( T4) , 1 h and 3 h after ICU administration ( T5 and T6) . Results There was no significant difference of rewarming time, extuba-tion time and peri-operative RBC transfusion among the three groups ( P>0.05). Compared with group A and B, group C had larger priming volume ( P<0.05) . Hemoglobin ( Hb) concentrations at T1 and T2 were lower in group C. Conclusion The application of de-creasing priming volume for low-weight adults can mitigate hemodilution and reduce the probability of peri-operative RBC transfusion.
Keywords：Extracorporeal circulationBlood conservation
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 162-164 )