Effect Analysis of Huayu Xiaozheng Decoction Combined with Mifepristone and Methotrexate in the Treatment of Ectopic Pregnancy

HUANG Caiqiao

doi:10.3969/j.issn.1672-7185.2025.05.006

Abstract：Objective To explore the effect of Huayu Xiaozheng Decoction combined with mifepristone and methotrexate in the treatment of ectopic pregnancy.Methods A total of 60 ectopic pregnancy patients treated with mifepristone combined with methotrexate at the Sixth People's Hospital of Nanhai District,Foshan City from March 2023 to March 2024 were selected as the Western medicine group,and another 60 ectopic pregnancy patients treated with Huayu Xiaozheng Decoction,mifepristone and methotrexate during the same period as the integrated traditional Chinese and Western medicine group.Compare the disappearance time of symptoms,the occurrence of adverse reactions,the Traditional Chinese Medicine(TCM)syndrome scores,negative emotions and quality of life before and after treatment between the two groups.Results The disappearance time of abdominal pain,lump,vaginal bleeding,and serum β-human chorionic gonadotropin conversion time in the integrated traditional Chinese and Western medicine group were significantly shorter than those in the Western medicine group(P<0.05).After treatment,both groups showed significant improvement in TCM symptom scores,negative emotion scores,and quality of life scores compared to before treatment(P<0.05).Moreover,after treatment,the above indicators in the integrated Chinese and Western medicine group were significantly better than those in the Western medicine group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Adding Huayu Xiaozheng Decoction to conventional Western medicine for ectopic pregnancy has better effcacy than using Western medicine alone,and can further improve patients'negative emotions and quality of life.It is worth promoting and using.