The Application Value of Serum Troponin I Combined with Heart-type Fatty Acid Binding Protein Detection in the Diagnosis of Myocardial Damage after Neonatal Asphyxia
Liu Lei
Abstract：Objective To investigate the diagnostic value of combined detection of serum troponin I(cTnI)and heart-type fatty acid-binding protein(H-FABP)in myocardial injury after neonatal asphyxia.Methods A study was conducted on 80 cases of asphyxia infants born in the obstetrics department of Danyang Maternal and Child Health Hospital from January 2020 to December 2022.Based on whether myocardial damage occurred in newborns after asphyxia,they were divided into a myocardial damage group of 28 cases and a non myocardial damage group of 52 cases.The risk factors for myocardial damage in newborns after asphyxia were screened by multiple logistic regression analysis,and the diagnostic value of single and combined detection of serum cTnI and H-FABP indicators was evaluated.Results The levels of cTnI and H-FABP in the myocardial injury group were higher than those in the non-myocardial injury group(P＜0.05).The logistic regression model analysis revealed that increased levels of cTnI and H-FABP were risk factors for myocardial injury after neonatal asphyxia(P＜0.05).The diagnostic efficiency of combined detection for myocardial injury after neonatal asphyxia was higher than that of individual detection of each indicator(P＜0.05).Conclusion The changes in serum cTnI and H-FABP levels have important diagnostic value for myocardial injury after neonatal asphyxia,and the combined detection of these two indicators can improve the diagnostic efficiency of myocardial injury after neonatal asphyxia.
Keywords：Serum Troponin IHeart-Type Fatty Acid Binding ProteinNeonatal AsphyxiaMyocardial DamageDiagnosis
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 61-63,67 )