The Therapeutic Effect of Bifidobacterium Quadruplex Live Bacterial Tablets Combined with Intermittent Phototherapy on Neonatal Hyperbilirubinemia
ZHANG Tingting
LV Yao
Abstract：Objective To explore the therapeutic effect of Bifidobacterium quadruplex live bacterial tablets combined with intermittent phototherapy on neonatal hyperbilirubinemia(NHB)in children.Methods Sixty children with NHB admitted to Anshun People's Hospital from January to December 2023 were randomly divided into a control group and a study group,with 30 cases in each group.The control group received intermittent phototherapy,while the study group received Bifidobacterium quadruplex live bacterial tablets in addition to the control group.The effects of different treatment methods on the recovery,bilirubin levels,and immune function of pediatric patients were compared.Results The time for jaundice resolution and treatment in the study group was shorter than that in the control group(P<0.05).One week after treatment,the total bilirubin,indirect bilirubin,and percutaneous jaundice index in the study group were lower than those in the control group(P<0.05).Follow up was conducted 4 weeks after discharge,and the CD3,CD4,IgA,IgG,and IgM levels in the study group were higher than those in the control group,and CD8 was lower than the control group(P<0.05).Conclusion The combination of Bifidobacterium quadruplex live bacterial tablets and intermittent phototherapy in the treatment of NHB can effectively accelerate the resolution of skin jaundice and the reduction of bilirubin,and has a certain immune regulatory function.
Keywords：Neonatal HyperbilirubinemiaBifidobacterium Quadruplex Live Bacterial TabletsIntermittent PhototherapyBilirubinImmunity
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 38-40,43 )