Comparison between Continuous Micro-Pump Infusion and Intravenous Infusion of Small Dose Insulin in the Treatment of Diabetes Ketoacidosis
HONG Huizhen
Abstract：Objective To compare the efficacy of continuous micro pump infusion and intravenous small dose insulin injection in the treatment of diabetes ketoacidosis(DKA).Methods Ninety DKA patients who admitted in Zhangzhou City Hospital from October 2021 to March 2023 were selected and divided into a control group and an observation group by random number table method,with 45 cases in each group.Both groups received low-dose insulin treatment.The control group received intravenous infusion,while the observation group received continuous infusion with a micro-pump.The treatment efficacy and adverse reactions between two groups of patients were compared.Results The time for blood glucose to reach the standard,urine ketone body to turn negative and blood pH recovery in the observation group were significantly shorter than those in the control group(P<0.05).After treatment,the fasting plasma glucose and 2-hour postprandial blood glucose in the observation group were lower than those in the control group(P<0.05).The malondialdehyde in the observation group was lower than that in the control group,while the superoxide dismutase was higher than that in the control group(P<0.05).The incidence of adverse reactions in the observation group was 4.44%,which was lower than the control group's 22.22%(P<0.05).Conclusion The use of a micro-pump to continuously pump insulin to treat DKA could improve clinical related indicators,lower blood sugar levels,improve stress response indicators,and reduce the occurrence of adverse reactions.
Keywords：Micro-PumpIntravenous InjectionInsulinLow DoseDiabetesKetoacidosis
Publication Date：2024-04-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 74-76 )