Analysis of Ultrasonic Features of Triple Negative Breast Cancer
WU Shanshan
Abstract：Objective To compare the ultrasonographic characteristics of triple-negative breast cancer(TNBC)and non-triple-negative breast cancer(NTNBC).Methods A total of 256 patients with breast cancer who were admitted to Yifu Hospital affiliated to Nanjing Medical University from January 2015 to December 2022 were collected.According to the expression of estrogen receptor(ER),progesterone receptor(PR)and human epidermal growth factor receptor-2(HER-2),they were divided into NTNBC group(196 cases)and TNBC group(61 cases).Results There were significant differences(P<0.05)in the size,shape,boundary,edge spicules,internal echo,internal calcification,posterior echo,and internal blood flow distribution of the lesions between the two groups.TNBC ultrasound images have regular shapes,mostly lobulated,circular,or quasi circular,and irregular shapes are relatively rare.The tumor has less infiltration into surrounding tissues,clear boundaries,and rare high echogenic spicules in the periphery.The internal echo of the tumor is low or mixed,and the calcification is mostly punctate microcalcifications.The internal vascular morphology is often punctate and branching.The posterior echo enhanced mostly.Conclusion There is a significant difference in ultrasound imaging between NTNBC and TNBC,and ultrasound can provide a basis for early differential diagnosis between them.
Keywords：Triple Negative Breast CancerUltrasoundCharacteristicsEstrogenProgesteroneHuman Epidermal Growth Factor Receptor-2
Publication Date：2024-03-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 36-38,42 )