Analysis of Serum 25-hydroxyvitamin D Levels in Patients with Heart Failure

DU Yanmei; YI Xin; DONG Ping

doi:10.3969/j.issn.1672-7185.2024.01.018

Abstract：Objective To explore the characteristics of serum 25-hydroxyvitamin D levels in patients with heart failure.Methods A total of 198 patients with heart failure who underwent treatment in the cardiovascular department of Beijing Huimin Hospital from June 2018 to March 2023 were selected as the heart failure group,and 200 healthy individuals who underwent health examinations in our hospital during the same period were selected as the health group.Compare the general information and serum 25-hydroxyvitamin D levels between the heart failure group and the health group.The serum 25-hydroxyvitamin D levels were compared in different functional grades in the heart failure group,as well as the incidence of cardiovascular adverse events in discharged individuals with different serum 25-hydroxyvitamin D levels in the heart failure group were compared after 6 months follow-up.Results There was no significant difference in general information between the heart failure group and the health group(P>0.05).The serum 25-hydroxyvitamin D levels in patients of heart failure group were significantly lower than those in the health group(P<0.05).The serum 25-hydroxyvitamin D levels in patients of heart failure group showed a significantly decreasing trend with the increase of heart function grading and the decrease of heart function(P<0.05).After 6 months of discharge,the incidence of cardiovascular adverse events in patients of heart failure group showed a significantly increasing trend with a decrease in serum 25-hydroxyvitamin D levels(P<0.05).Conclusion The serum 25-hydroxyvitamin D levels in patients with heart failure are lower than those in healthy individuals,and as the patient's condition worsens and cardiac functional declines,the serum 25-hydroxyvitamin D levels show a downward trend,and the incidence of cardiovascular adverse events increases.Therefore,the serum 25-hydroxyvitamin D levels should be evaluated in patients with heart failure.For those with insufficient 25-hydroxyvitamin D,timely supplementary intervention should be given to reduce the risk of cardiovascular adverse events and improve patient prognosis.