Correlation Analysis between Mycoplasma and Chlamydia Infection in Female Reproductive Tract and HPV Infection

WEI Beiyu; ZHOU Xiang

doi:10.3969/j.issn.1672-7185.2024.01.012

Abstract：Objective To explore the correlation between female reproductive tract infections of mycoplasma and chlamydia and human papilloma virus(HPV)infection.Methods A total of 168 female patients who underwent HPV-DNA genotyping testing at Changzhou Maternal and Child Health Care Hospital from June to December 2022 were selected as the research subjects.According to the results of HPV-DNA genotyping,the group was divided into HPV infected group and non-HPV infected group.Baseline data,vaginal environmental indicators,and infections of mycoplasma and chlamydia in the reproductive tract were compared between the two groups.Multivariate logistic regression analysis was used to analyze the risk factors for HPV infection.Results The proportion of HPV infected individuals with education level of junior high school or below,age of first sexual intercourse≤20 years old,number of sexual partners≥2,history of sexual transmission,positive rates of various indicators in the vaginal environment,and infection rates of mycoplasma and chlamydia in the reproductive tract were significantly higher than those in the non-HPV infected group(P<0.05).Multivariate logistic regression analysis showed that the risk factors for HPV infection include education level of junior high school or below,age of first sexual intercourse≤20 years old,number of sexual partners≥2,history of sexual transmission,positive hydrogen peroxide,positive leukocyte esterase,positive salivary glycosidase,as well as mycoplasma and chlamydia infections.Conclusion Female reproductive tract infections of mycoplasma and chlamydia are associated with the occurrence of HPV infection.