Effect of Depth of Anesthesia on Brain Metabolism in Adult Patients undergoing General Anesthesia for Abdominal Surgery
WU Xiaoliang
Abstract：Objective? To observe the effect of depth of anesthesia on brain metabolism. Methods? A total of 150 patients who underwent abdominal surgery in our hospital from 2017 to 2019 were randomly divided into shallow anesthesia group and deep anesthesia group, 75 cases in each group. The depth of anesthesia was monitored by bispectral electroencephalogram index (BIS) during the operation. The BIS of shallow anesthesia group was 50~59, and that of deep anesthesia group was 30~39. The cerebral extraction ratio for oxygen (CERO2) of cerebral arteriovenous O2 content difference (Da-jvO2) before anesthesia induction (T0), before intubation (T1), after intubation (T2), before operation (T3), after operation (T4) and during extubation (T5) were compared between the two groups. Results? There were significant differences in Da-jvO2 and CERO2 between shallow anesthesia group and deep anesthesia group at different time points (P<0.05). There was no significant difference in Da-jvO2 and CERO2 between shallow anesthesia group and deep anesthesia group at T0 time point (P>0.05), while there were significant differences in Da-jvO2 and CERO2 at other time points (P<0.05). Conclusion? There is a certain relationship between the depth of anesthesia and the level of brain metabolism, that is, the deeper the degree of anesthesia, the lower the level of brain metabolism.
Keywords：Depth of AnesthesiaAbdomenSurgeryBrain MetabolismInfluence
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 63-65,68 )