Result Analysis of Serum CoxA16-IgM and EV71-IgM in 25 490 Children with Hand, Foot and Mouth Disease
LAN Xiane
OUYANG Hui
HUANG Meiqiong
Abstract：Objective? To retrospectively analyze the levels of serum CoxA16-IgM and EV71-IgM in children with hand, foot and mouth disease. Methods A total of 25 490 children with hand, foot and mouth disease diagnosed in our hospital were selected. Serum CoxA16-IgM and EV71-IgM were examined and analyzed in all children. Results A total of 1 715 cases (6.73%) were positive for CoxA16-IgM, 3 617 cases (14.19%) were positive for EV71-IgM, and 182 cases (0.71%) were double positive for CoxA16-IgM and EV71-IgM. There was significant difference between the positive rates of CoxA16-IgM and EV71-IgM (χ2=757.72, P<0.05). The positive rate of antibody in male and female children was significantly different, 30.15% of male and 11.60% of female, respectively (χ2=1 325.91, P<0.05). The positive rates of CoxA16-IgM and EV71-IgM were the highest in 2~3 years old group. Conclusion Coxsackievirus A16 and EV-71 are the most common types of hand, foot and mouth disease in children, especially in the age group of 2~3 years, which is the high incidence stage of hand, foot and mouth disease.
Keywords：[Key Words] HandFoot and Mouth DiseaseCoxA16-IgMEV71-IgMChildren
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 58-60 )