Comparison of Effects between General Anesthesia and Combined Spinal Epidural Anesthesia on Cognitive Function in Lung Cancer Patients Undergoing Radical Resection
XIAO Liguo
Abstract：Objective? To compare the effects of general anesthesia and combined spinal-epidural anesthesia on cognitive function in lung cancer patients undergoing radical resection. Methods From 2016 to 2018, 85 lung cancer patients undergoing radical resection were randomly divided into observation group (43 cases) and control group (42 cases). The observation group was given combined spinal-epidural anesthesia, while the control group was given general anesthesia. The cognitive function at different time points after operation was compared with the Mini Mental State Examination (MMSE) between two groups. were used to evaluate pain degree and lumbar function before and after treatment. Results The MMSE score of both groups gradually recovered. At the T4 time point, MMSE score was close to normal in observation group, while at the T5 time point in control group, MMSE score was close to normal. There were significant differences in MMSE scores of T1, T2, T3 and T4 time point between the two groups (P<0.05), and no significant differences were found in T0 and T5 time point between two groups (P>0.05). Conclusion The effect of combined spinal-epidural anesthesia on postoperative cognitive function is less than that of general anesthesia, but the effect of the two anesthesia methods is mainly concentrated on the short-term, and can be well recovered.
Keywords：Lung CancerRadical ResectionCognitive FunctionGeneral AnesthesiaCombined Spinal-epidural
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 69-70 )