Clinical Pathological Analysis of 236 Eyelid Masses with Skin Ulcer

ZHANG Yang; LIU Jinzhao

doi:10.3969/j.issn.1672-7185.2019.02.020

Abstract：Objective? To improve diagnostic accuracy for patients with eyelid masses through analyzing the clinicopathological characteristics and pathogenesis of eyelid masses with skin ulcer. Methods A total of 236 cases of eyelid masses with skin ulcer were screened from 4 315 cases via looking up the electronic medical records. Clinical manifestations and histological characteristics were reviewed. Relevant literatures were reviewed. Results Of 236 eyelid masses with skin ulcer, benign eyelid masses were 125 cases (52.97%), the top three in the ranking were granulation tissue (58 cases), keratoacanthoma (21cases), and seborrheic keratosis (17 cases); malignant eyelid neoplasms were 111 cases (47.03%), the top three in the ranking were basal cell carcinoma (62 cases), sebaceous carcinoma (23 cases), squamous cell carcinoma(19 cases). In benign masses, 3.40% of eyelid masses were accompanied by skin ulcer, in malignant masses, 17.40% of eyelid neoplasms were accompanied by skin ulcer; and 5.47% of all eyelid masses were accompanied by skin ulcer. Different types of eyelid masses were induced by the same cause. Conclusion The pathological types of eyelid masses with skin ulcer are various. Although both benign and malignant masses can develop skin ulcers, the incidence of malignant tumors is higher. In order to ensure the accuracy of diagnosis and reduce the rate of misdiagnosis, the diagnosis should be made on the basis of clinical features and pathological examination.