The Value of Base Excess Difference and Lactate Clearance Rate in Evaluating the Prognosis of Adult Patients with Shock in ICU

TAN Guojia; SONG Yan

doi:10.3969/j.issn.1672-7185.2019.01.020

Abstract：Objective To evaluate the value of base excess difference and lactate clearance rate in the prognosis of adult patients with shock in ICU.Methods The clinical data of 36 adult patients with shock in ICU in Central Hospital Affiliated to Shenyang Medical College from January to November 2017 were analyzed retrospectively.The patients were divided into survival group and death group,and the value of base excess difference and lactate clearance rate between two groups were analyzed to evaluate the prognosis.Results There was no significant difference between survival group and death group in base excess and arterial blood lactate when admitted into ICU and 12 hours after admission(P > 0.05).The difference in base excess and arterial blood lactate between admitted ICU and after 12 hours admitted into ICU was significant different in survival group(P < 0.05).There was no significant difference in base excess and arterial blood lactate between admitted ICU and after 12 hours admitted into ICU in death group(P > 0.05).There were significant differences in base excess difference and lactate clearance rate after 12 hours admitted into ICU between survival group and death group (P < 0.05).After 12 hours admitted into ICU,the base excess difference were negatively correlated with lactate clearance rate.The areas under the ROC curves of base excess difference and lactate clearance rate were 0.785 and 0.867 for prediction of death in shock patients,respectively.Conclusion The base excess difference and lactate clearance rate after 12 hours admitted into ICU are good markers for evaluating the prognosis of shock patients in ICU.