Diagnostic Value of Seminal Plasma Elastase Level in Male Infertility Caused by Genital Tract Infection
YOU Xuehua
MEI Xiaoyan
LI Jingmei
WANG Zhihua
LIN Tianshou
Abstract：Objective To investigate the diagnostic value of seminal plasma elastase level in male infertility caused by genital tract infection. Methods A total of 303 male infertility patients with suspected infection were selected from the reproductive center, Fuzhou General Hospital of Nanjing Military Region from January 2016 to December 2016. The levels of elastase in seminal plasma and semen quality were detected in all patients. The relationship between elastase levels in seminal plasma and semen quality was analyzed by grouping the patients according to infection status, and the diagnostic value of elastase levels in seminal plasma was evaluated in infertility patients caused by male genital tract infection. Results There were significant differences in sperm density, motility, A + B motility, semen liquefaction time and sperm deformity rate between the infected and non-infected groups(P<0.05), and the differences were gradually greater with seminal plasma elastase level increases. The sensitivity and specificity were 0.83 and 0.41 at cut-off value of 290 ng/mL, respectively. The cut-off value of 1 000 ng/mL had a sensitivity of 0.72 and a specificity of 0.71. But the sensitivity and specificity had a tendency of decrease with the seminal plasma elastase level increase. Conclusion The elastase level in seminal plasma is closely related to the sperm quality. It is of great value in the diagnosis of infertility caused by male genital tract infection.
Keywords：InfertilityMaleDiagnosisSeminal Plasma ElastaseReproductive Tract Infection
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 56-58 )