Observation of the Curative Effect of Clindamycin in the Treatment of Orthopaedic Methicillin-resistant Staphylococcus Aureus Infection
WANG Liang
Abstract：Objective To observe the curative effect of clindamycin in the treatment of orthopedic methicillin-resistant Staphylococcus aureus infection.MethodsRetrospective analysis was performed on the patients with methicillin resistant Staphylococcus aureus infection in Department of Orthopedics of Shenyang No. 245 Hospital from August, 2014 to August, 2015. The observation group took clindamycin, while the control group took vancomycin. The curative effects of two groups were compared.ResultsThe differences between the two groups in the cure rate and the clearance rate of Staphylococcus aureus were not statistically signiifcant (P > 0.05). There were 4 cases of phlebitis and 2 cases of allergic reaction characterized by rash in the control group during the treatment. There was one case of gastrointestinal reaction with the main manifestation of nausea and diarrhea and one case of allergic reaction characterized by rash in the observation group.ConclusionClindamycin is equivalent to vancomycin in the therapeutic effect of orthopedic methicillin-resistant Staphylococcus infection treatment, but for clindamycin there is lower incidence of adverse reactions.
Keywords：OrthopedicsInfectionClindamycinVancomycin
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 48-49 )