The Influence of Short-term Intensive Treatment on Pancreatic Function by Insulin Pump to Type 2 Diabetes Mellitus with Different Course of Disease
Lin Xiaoyue
Abstract：Objective To observe the influence of short-term intensive treatment on pancreatic function by insulin pump to Type 2 Diabetes Mellitus (T2DM) with different course of disease. Methods 183 cases of T2DM were col ected and divided into GroupⅠ(60 cases, new diagnosed and without any treatment), GroupⅡ(60 cases, course of disease≤3 years) and GroupⅢ(63 cases, course of disease>3 years). All the patients accepted intensive treatment by insulin pump. We compared the fasting plasma glucose (FPG), 2-hour postprandial blood glucose (2 h PG), C-peptide, the improvement rate of Homa-βand Homa-IR. Results The FPG, 2 h PG, C-peptide were improved in each group compared to those before the treatment (All P<0.05). The function ofβcells and insulin resistance were improved in each group after the treatment with statistical significance (All P<0.05). Conclusion Short-term intensive treatment by insulin pump could improve the function ofβcells and insulin resistance in pancreas. The patients with shorter course of disease could benefit more from it. So, we suggest that the patients with T2DM should accepted short-term intensive treatment by insulin pump if it is possible.
Keywords：diabetes mellitusType 2insulin pumpinsulin resistanceintensive treatment
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 22-23,24 )