The clinical effect of 38 cases treated with one anastomosis gastric bypass for the treatment of type 2 diabetes
BIAN Shi-bo
ZHANG Yi-qiao
LI Meng-yi
TIAN Pei-rong
ZHANG Meng
LIU Jia
LIU Jing-li
ZHANG Peng
LIU Yang
ZHANG Zhong-tao
Abstract：Objective To evaluate the clinical effect of one anastomosis gastric bypass(OAGB)for the treatment of type 2 diabetes mellitus(T2DM).Methods A retrospective analysis was performed on data from 38 T2DM patients who underwent OAGB between January and August 2023 with a 1-year follow-up at Beijing Friendship Hospital.Changes in body weight,glycemic control,metabolism related indicators and gastroscopy findings before and after surgery were compared.Logistic regression was used to analyze the factors influencing complete T2DM remission.Results A total of 38 patients were included.The percentage of total weight loss(％TWL)and percent of excess weight loss(％EWL)of the patients at 1 year after surgery were(28.6±7.1)％and(124.6±57.9)％,respectively.The mean body mass index(BMI)decreased from 35.1±6.1 to 25.0±4.1 and mean glycated hemoglobin A1c(HbA1c％)decreased from(9.1±1.5)％to(5.6±1.0)％.All the above differences were statistically significant(P＜0.001).The level of total cholesterol,triglycerides,low-density lipoprotein and y-glutamyl transferase was reduced significantly after surgery than those before surgery(all P＜0.001).The complete T2DM remission rate was 65.8％(25/38)and was linearly related to the ABCD score(P=0.015).Duration(OR=0.829,P=0.016)and％TWL(OR=1.137,P=0.039)were independent factors influencing complete remission.Postoperative rates of anemia,hypoalbuminemia and bile reflux were 18.4％,13.2％and 31.3％,respectively,significantly higher than preoperative rates(all P＜0.001).Conclusion OAGB is an effective and safe treatment for T2DM.However,attention should be given to postoperative anemia,hypoalbuminemia and bile reflux.
Keywords：one anastomosis gastric bypasstype 2 diabetes mellitusclinical effect
Publication Date：2025-07-01
Online Publishing Date：2025-09-04(First online date of this platform, not the publication date of the document)
Pages：6( 826-831 )