Conceptual update and clinical practice of pelvic exenteration
GU Jin
HONG Hao-peng
Abstract：In recent years,multicenter studies on pelvic exenteration(PE)have been widely reported internationally,achieving encouraging long-term survival outcomes and leading to changes in the surgical concept.The primary goal of PE is to achieve complete(R0)resection and en bloc removal of tumor-invaded pelvic organs,aiming to improve patient survival rates and quality of life.For patients with locally advanced tumors,systemic chemotherapy or local radiotherapy can transform tumors that were initially unresectable into resectable ones,creating conditions for PE.Compared to neoadjuvant therapy,adjuvant therapy can better improve postoperative long-term survival for some PE patients.Although PE can significantly improve the survival rate and quality of life for certain patients with locally advanced or recurrent pelvic malignancies,its high risk of complications requires comprehensive preoperative assessment and preparation.Postoperatively,close collaboration and comprehensive treatment from a multidisciplinary team(MDT)are necessary to minimize the incidence and severity of complications as much as possible.
Keywords：pelvic exenterationoverall survivalcomplication
Publication Date：2025-01-31
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 59-64 )