Comparison study on gastroesophageal reflux disease after sleeve gastrectomy and sleeve gastrectomy with transit bipartition
YAO Li-bin
YU Ying-hua
LI Sheng-li
WANG Jian
HONG Jian
SHAO Yong
ZHU Xiao-cheng
Abstract：Objective To compare the incidence and relief of gastroesophageal reflux disease(GERD)after sleeve gastrectomy(SG)versus sleeve gastrectomy with transit bipartition(SG-TB).Methods A retrospective analysis was conducted on the clinical data of 195 patients who underwent SG or SG-TB surgery at the Affiliated Hospital of Xuzhou Medical University from January to December 2022 were retrospectively analyzed.All patients were divided into SG groups(n=96)and SG-TB groups(n=99)based on the surgical procedure.The total followed up time was 12 months.Preoperative baseline data and postoperative weight changes were compared between the two groups.The incidence and relief of postoperative GERD and esophagitis were compared based on GERD-Q scores and gastroscopy results.The influencing risk factors of the postoperative new GERD were analyzed by logistic regression.Results There were no significant statistical differences in preoperative age,gender,weight,BMI,or the prevalence of hypertension or hyperlipidemia between the two groups(P＞0.05).The SG group had lower preoperative rates of GERD and T2DM than the SG-TB group,and the difference was statistically significant(P＜0.05).12 months after surgery,the total weight loss percentage(％TWL)[(30.5±6.3)％vs.(35.9±7.8)％,P＜0.001)]and the excess weight loss percentage(％EWL)[(85.8±22.1)％vs.(106.5±27.2)％,P＜0.001)]in the SG group was significantly lower than that in the SG-TB group,and the difference was statistically significant;the remission rate of GERD in the SG-TB group was significantly higher than that in the SG group(85.0％vs.22.2％,P=0.002),and the new incidence rate of GERD was lower than that in the SG group(7.6％vs.25.3％,P=0.002);there was no significant difference in remission rate and new incidence rate of esophagitis between the two groups(P＞0.05).Logistic regression analysis indicated that SG was an independent risk factor for new postoperative GERD(OR=2.725,95％CI 1.120-6.633,P=0.027).Conclusion Compared to SG,SG-TB surgery can significantly alleviate preoperative GERD and reduce the rate of new-onset GERD postoperatively.For obese patients with preoperative GERD,SG-TB surgery can be considered.
Keywords：sleeve gastrectomysleeve gastrectomy with transit bipartitiongastroesophageal reflux diseaseobesity
Publication Date：2024-08-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 911-915 )