Treatment strategies for colorectal liver oligometastases
HUANG Gang
YU Jian
ZHOU Wei-ping
Abstract：Colorectal liver oligometastasis(CRLOM)refers to the controlled(already resected or resectable)primary colorectal cancer with a limited number of liver metastases that can be safely and effectively treated locally.The incidence rate of CRLOM is high but its prognosis is poor.At present,comprehensive treatment strategies based on surgery are mainly used,including conversion therapy,neoadjuvant therapy,resection of liver metastases,postoperative adjuvant therapy,etc.Among them,conversion therapy is divided into residual liver volume(FLR)conversion and oncological conversion,and FLR conversion includes portal vein embolization(PVE),portal vein ligation(PVL),associated liver partition and portal vein ligation for staged hepatectomy(ALPPS)and liver vein deprivation(LVD).Local treatment measures such as ablation,transcatheter intra-arterial therapy,and radiation therapy can be applied to improve the surgical efficacy of CRLOM or unresectable CRLOM.Liver transplantation has a good therapeutic effect on patients with unresectable CRLOM who have undergone strict screening.To develop personalized treatment strategies,the actual situation of CRLOM patients should be taken into consideration.
Keywords：colorectal liver metastasessurgerycomprehensive treatment
Publication Date：2024-07-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 761-767 )