Surgical diagnosis and treatment of thyroid cancer with lung metastasis
LI Jian-bo
ZHANG De-guang
Abstract：Thyroid cancer is a common malignancy within the endocrine system,and its incidence has been rising annually.Based on tissue origin,thyroid cancer can be classified into differentiated thyroid cancer(DTC),medullary thyroid cancer(MTC),and anaplastic thyroid cancer(ATC).These types of thyroid cancer vary in terms of differentiation,oncological behavior,and aggressiveness,which also leads to differences in diagnosis,treatment,and prognosis.The lungs are the most common site of distant metastasis for thyroid cancer,especially DTC.Although DTC is relatively less malignant,5.2％of patients still experience lung metastasis.MTC and ATC are more malignant and aggressive,making them more likely to metastasize to the lungs.Early diagnosis and standardized treatment are crucial for improving patient quality of life and reducing mortality rates.Surgical resection of pulmonary metastases can yield favorable survival rates,but surgery may not be feasible for patients with multiple or diffuse metastases or distant metastases to other sites.In such cases,treatment options include radioactive iodine-131 therapy,TSH suppression,targeted therapy,and radiochemotherapy.The treatment of thyroid cancer lung metastasis requires a comprehensive consideration of tumor type,the extent of metastasis,and individual patient circumstances to formulate a reasonable treatment plan.
Keywords：thyroid cancerdifferentiated typelung metastasissurgical treatmentdiagnostic methodsthyroid medullary carcinomathyroid undifferentiated carcinomasurvival rate
Publication Date：2024-06-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 705-708 )