The application of ultrasound-guided percutaneous transhepatic injection of indocyanine green and sonovue mixture in laparoscopic liver cone-unit resection
CHENG Dong-hui
YANG Chong
JIANG Ji-peng
ZUO Bang-you
CAO Wen-bin
WU Hao
YANG Wen-hao
YOU Xin-yu
ZHANG Yu
Abstract：Objective To investigate the application value of ultrasound-guided percutaneous transhepatic injection of indocyanine green and sonovue mixture in laparoscopic liver cone-intersection.Methods A total of 16 patients with hepatocellular carcinoma who were admitted to the Sichuan Provincial People's Hospital from January 2022 to May 2023 were retrospectively analyzed.All of them underwent ultrasound-guided percutaneous transhepatic injection of indocyanine green and sonovue mixture in laparoscopic liver cone-unit resection.Observation indicators include tumor fluorescence imaging,cone unit fluorescence staining,perioperative indicators of patients,and follow-up.Results All 16 patients successfully displayed the tumor boundary using ICG fluorescence,and the liver cone-unit ICG fluorescence imaging included the tumor completely.Among them,15 patients had a liver cone-unit fluorescence boundary that was more than 1cm away from the tumor boundary,and 1 patient was about 0.5cm.Postoperative anatomical specimens with a cutting edge of 0.5-1.6 cm.Among 16 patients,3 patients underwent puncture of 2 portal veins,and 13 patients underwent puncture of 1 portal vein,similar to preoperative evaluation.The surgical duration ranges from 62 to 121 minutes,with a median duration of 89 minutes.Intraoperative bleeding was 30-110 mL,with a median bleeding volume of 80 mL.There was no intraoperative blood transfusion or conversion to open surgery.No patients had recurrence after operation,up to July 12,2023,when the follow-up period ranged from 2 to 14 months.Conclusion Ultrasound-guided percutaneous transhepatic injection of a mixture of indocyanine green and sonovue-assisted laparoscopic liver cone-unit resection is safe and feasible.Its long-term effect on liver malignant tumors is worth further study.
Keywords：liver cone-unithepatectomylaparoscopyfluorescence imagingindocyanine greensonovue
Publication Date：2024-02-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 211-215,223 )