From technology to strategy-focus on hot issues of pancreatic cancer treatment in 2023
LIU Guang-nian
TIAN Xiao-dong
YANG Yin-mo
Abstract：Pancreatic cancer has the worst prognosis among all gastrointestinal tumors.The development of multidisciplinary comprehensive diagnostic and treatment models for pancreatic cancer in the context of systemic therapy has had a profound impact on pancreatic surgery.Significant progress has been made in surgical techniques,with notable improvements in surgical safety and resection rates.Minimally invasive surgery is gradually becoming the future trend in pancreatic surgery.Neoadjuvant therapy is becoming increasingly popular and standardized,and are now the standard treatment modalities for patients with borderline resectable and locally advanced pancreatic cancer.The dawn of immune and targeted therapies is emerging,yet sensitive targets are still lacking,characterizing pancreatic cancer as an"immune-cold tumor."There is an urgent need for breakthroughs and translation in basic research on pancreatic cancer.A deeper understanding of its biology and accurate oncological evaluations are fundamental in guiding clinical decisions and improving long-term prognosis for patients with pancreatic cancer.
Keywords：pancreatic cancerpancreaticoduodenectomyneoadjuvant therapyimmunotherapymolecular classification
Publication Date：2024-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 74-78 )