Consensus and controversy on the radical resection range of pancreatic cancer
LOU Wen-hui
FANG Yuan
Abstract：Pancreatic cancer has the worst prognosis in all the digestive malignant tumors.Local recurrence,lymph node and distant metastasis are the key prognostic factors and resection range of pancreatic cancer has been gone through 3 stages:first stage was the improvement of surgical safety from Doc Whipple performed the first pancreaticoduodenectomy to the 1960s;the next stage was the extended pancreatectomy including extended lymphadenectomy,combined vascular resection and reconstruction,and total pancreatectomy;recently the resection range has changed to standard lymphadenectomy since the RCT results did not show survival benefit after 2000.Although expert consensus had been reached on the radical resection range of pancreatic cancer,the efficacy was not satisfied.Surgeons need to understand the biological behavior of pancreatic cancer and pay attention to the value of combined chemoradiotherapy.
Keywords：pancreatic cancerpancreaticoduodenectomylymphadenectomyprognosis
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 146-148 )