The optimal time for surgery of locally advanced pancreatic carcinoma treated with neoadjuvant chemotherapy
Abstract：Neoadjuvant therapy is often used in locally advanced pancreatic carcinoma patients in order to down tumor stage, and increase the resectability. However, for the optimal time for surgery after neoadjuvant therapy is still controversy. Surgical resection is recommended for patients who have undergone successful neoadjuvant therapy with reduced stage. Combining prospective and retrospective studies and neoadjuvant treatment data from the authors' center, the paper suggests that the optimal time for surgery is 4-8 weeks after 4-6 cycles of neoadjuvant therapy. For the choice of surgical approach, laparoscopic exploration can be considered to confirm whether metastatic diseases exist and preliminary identification of resectability as well, then for further surgical resection.
Keywords：advanced pancreatic carcinomaneoadjuvant therapyoptimal time for surgery
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 748-751 )