Application and evaluation of neoadjuvant therapy in locally advanced pancreatic carcinoma
ZHANG Tai-ping
CAO Zhe
ZHAO Yu-pei
Abstract：Radical resection is the effective means to prolong survival time of patients with pancreatic carcinoma. However, 40% of the patients are diagnosed with locally advanced pancreatic carcinoma in the first clinic. Individualized neoadjuvant treatment is expected to bring the stage-down of locally advanced pancreatic carcinoma,in order to gain the chance of radical excision. But the specific treatment is still controversial. Neoadjuvant chemotherapy followed by sequential chemoradiotherapy is the most common strategy in the neoadjuvant therapy. Gemcitabine plus nab-Paclitaxel and FOLFIRINOX are expected to be the best chemotherapy regimens.
Keywords：locally advanced pancreatic carcinomaneoadjuvant therapy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 744-748 )