Individualized treatment of advanced pancreatic carcinoma with special reference to liquid biopsy
LOU Wen-hui
LIU Xiao-yu
Abstract:The advantage of liquid biopsy in pancreatic cancer lies in minimal invasive, repeatable, and coherent to pathological diagnosis. Circulating tumor cells (CTCs) and Circulating cell-free DNA (cfDNA) are the major parts of liquid biopsy, there will be good perspertive in the personalized therapy of pancreatic cancer. Standardized technique, reasonable interpretation of the result will be the fundation of liquid biopsy in pancreatic cancer. Dynamically monitoring the change of CTC and cfDNA will provide clue for discovering new markers of recurrence and metastasis, as weill as new target of treatment.
Keywords:advanced pancreatic carcinomaliquid biopsycirculating tumor cellscirculating cell-free DNA
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 728-730 )
Chinese Journal of Practical Surgery

Chinese Journal of Practical Surgery

PKUISTIC
ISSN:1005-2208
Year, Vol.(Issue):2017,37(7)