Surgical intervention and prognostic factor analysis of colorectal peritoneal carcinomatosis：A retrospective analysis of 75 consecutive cases
Abstract：Objective To explore risk factors associated with survival for patients who underwent surgery for colorectal peritoneal carcinomatosis. Methods The clinical and follow-up data of 75 patients who underwent surgery for colorectal peritoneal carcinomatosis at the Sixth Affiliated Hospital of Sun Yat-Sen University from January 2011 to January 2015 were analyzed retrospectively. The influence of surgery on the prognosis was evaluated. Results The overall median survival time was 18.6 months. The median survival time of the complete cytoreduction group,the incomplete cytoreduction and the palliative surgery group (diversion only or bypass surgery) were 38.2,10.4 and 10.4 months, respectively; compared with the palliative surgery group,the complete cytoreduction had significant survival benefit (P<0.001),whereas the incomplete cytoreduction had not (P=0.524). The results of multivariate analysis demonstrated that PCI<20,complete cytoreduction and peritoneal carcinomatosis alone were independent good prognostic factors. Complication incidence (Clavien-Dindo≥2) of the incomplete cytoreduction group and the palliative surgery group were 22.2% and 0 respectively; 30-day mortality were 7.4% and 0. Conclusion Patients performed complete cytoreduction have a relative good prognosis. Compared with palliative surgery,incomplete cytoreduction fails to improve patient prognosis.
Keywords：colorectal neoplasmperitoneal carcinomatosisprognostic factor analysis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1215-1219 )