Next-generation sequencing assistants in diagnosis of testicular metastatic adenocarcinoma after gastric cancer surgery
CAO Yan-shuo
SUN Li
SHEN Lin
Abstract：Objective To investigate the role of next-generation sequencing technique in the diagnosis and treatment of cancer. Methods Using traditional pathologic diagnosis and next-generation sequencing and molecular evolutionary genetics analysis (MEGA) in a patient who was diagnosed of testicular metastatic adenocarcinoma 7 years after the radical surgery of gastric cancer. Results Pathologists make the conclusion that testicular tumor is the metastasis from gastric cancer, while the results of sequencing indicates that there may be other potential original tumor instead of gastric cancer from 7 years ago. Conclusion New gene detection technique has challenged the conclusion of traditional histopathology, and there is necessity to accumulate more data in future research to better apply this technique in clinical practice.
Keywords：next-generation sequencingmolecular evolutionary genetics analysisgastric cancertesticular metastasistesticular tumor
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 970-973 )