Locoregional surgical strategies of stage IV breast cancer
ZHAO Yan
ZHENG Xin-yu
Abstract：Systemic therapy is the mainstream treatment ofstage IV breast cancer. Current guidelines do not recommendlocoregional surgery for Stage Ⅳ breast cancer despite mostretrospective studies suggesting a survival benefit. Surgicalexcision of the primary breast cancer tumor in the presence ofsynchronous metastatic disease is debated since limitedprospective, randomized studies showing that surgicaltreatment of primary tumors in woman presenting with stage IVdisease does not produce an increase in OS. However, theauthor suggests the situation could be treated individually,initial surgery could be done for those women requiringpalliation of symptoms or with impending complications, suchas skin ulceration, bleeding and pain if complete localclearance of tumor may be obtained and if other sites ofdisease are not immediately threatening to life, especiallywhen it is offered in a multimodality treatment program andwith the preference of patients.
Keywords：stage Ⅳ breast cancerlocoregional surgerysystemic therapy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 713-718 )