Hepatic dysplastic nodules:A management and prognostic analysis of 20 cases
Abstract：Objective To summarize the clinical and pathological characteristics as well as management experience of hepatic dysplastic nodule (HDN). Methods The clinical data and follow-up results of 20 cases of HDN treated from October 2002 to December 2014 in Peking Union Medical College Hospital were analyzed retrospectively. Results All cases underwent operation,and the postoperative recovery was good. In postoperative pathological examination,only 1 case of tumor boundary was ambiguous;12 cases combined with liver cirrhosis. Pathological diagnosis:10 cases of simple HDN,1 case of HDN complicated with focal nodular hyperplasia,7 cases of HDN complicated with HCC,1 case of HDN complicated with focal lesions,1 case of HDN complicated with liver cell adenoma. In the postoperative follow-up,1 case was lost. 5 cases of HDN complicated with canceration recurrented hepatocellular carcinoma after 6-24 months. The rest of the cases were followed up to January 2015 without recurrence. Conclusion HDN might be a precancerous lesion with relatively good prognosis while carcinogenesis would change prognosis. So the intensive following-up is necessary. Medical history,tumor markers and imaging are helpful for the diagnosis. Surgical resection should be considered when nodules are difficult to differentiate or hepatocarcinogenesis have occurred.
Keywords：liver tumordysplastic nodulehepatocellular carcinomahepatectomy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 525-527 )