Clinical pathological characteristics of double primary cancers of gastric cancer and breast cancer:A report of 25 cases
Abstract：Objective To investigate clinicopathological characteristics of double primary cancers of gastric cancer and breast cancer, so as to provide reference for following study of secondary primary tumor and (or) multiple primary cancers(MPC). Methods The clinicopathological data of 25 cases of double primary cancers of gastric cancer and breast cancer admitted from January 2001 to June 2013 in Beijing Cancer Hospital were analyzed. Among 25 cases, 6 cases had ovary carcinoma and (or) other malignant tumors. Results The middle onset age of the 1st primary cancer, mainly breast cancer, was 45 (30-66) years old, while that of the 2nd primary cancer was 54 (35-74) years old, mainly gastric cancer. The main pathology of gastric cancer was diffuse type accounting for 80%, while that of breast cancer was invasive ductal cancer accounting for 88%. The middle interval between the two cancers was 49(6.5-243.0)months. Conclusion Double primary cancers of gastric cancer and breast cancer have the characteristics of young onset age, short interval between two primary cancers and comorbidity with other primary cancers and family history, which indicates genetic susceptibility may play a role. For the treatment, early detection and early radical surgery can only prolong the survival.
Keywords：breast cancergastric cancerdouble primary cancermultiple primary cancerpathological characteristics
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 645-648 )