Multidisciplinary approach on the management of patients with advanced gastrointestinal neuroendocrine tumors
BAI Chun-mei
Abstract：The terminology of the new WHO classification of gastrointestinal neuroendocrine neoplasms (NENs) includes neuroendocine tumors (NET G1/G2) and neuroendocrine cancinoma(NEC G3). Gastrointestinal NENs are frequently metastatic at the time of initial diagnosis. Poorly-differentiated gastrointestinal NECs have a rapidly progressive clinical course and a poor prognosis. They are generally treated with platinum-based chemotherapy regimens. Therapeutic approaches for management of advanced gastrointestinal NENs include surgical, medical, local ablative/locoregional procedure and nuclear medicine strategies. Cytotoxics are not considered when the primary location is in the midgut. The initiating medical therapy with a somatostatin analog for advanced gastrointestinal NET patients is standard therapy.
Keywords：gastrointestinal neuroendocrine tumormultidis-ciplinary treatment
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 515-518 )