Current clinical practice of gastroenteropancreatic neuroendocrine neoplasm in China
TANG Cheng-wei
GUO Lin-jie
Abstract:The overall incidence of gastroenteropancreatic neuroendocrine neoplasm (GEP-NENs) is still unclear in China. The local incidence is about 1.86/105 annually which is slightly less than USA and European countries (3.3/105-5.25/105). The GEP-NENs in China are usually located in pancreas,rectum and appendix,while those in USA are mostly found in the small intestine,rectum,colon and pancreas. Most of GEP-NENs in China were nonfunctional. Approximately 10% of GEP-NENs are functional and mainly located in the pancreas. Carcinoid syndrome is rare in China when compared with the data from other countries. The data from Chinese literature reported that about 50% of GEP-NENs presented distant metastasis at diagnosis. It has been recommended that GEP-NENs less than 1cm in diameter should be resected with endoscopic submucosal dissection. Surgical resection is the best treatment for tumors larger than 1cm. Research and continuing education of GEP-NENs are increasingly concerned by Chinese clinicians.
Keywords:gastroenteropancreatic neuroendocrine neo-plasmepidemiological features
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 490-492 )
