The clinical significance of mutation detection in the gastrointestinal stromal tumors
Abstract：Gastrointestinal stromal tumor (GIST) is a specific clinicopathologic entity characterized by activating mutations of kit and PDFGR-α genes. The immunohistochemical staining is frequently used to confirm the diagnosis. However, the demonstration of kit and PDFGR-α mutations has been shown to be more reliable in establishing the clinical significance for application of imatinib and sunitinib.
Keywords：gastrointestinal stromal tumor (GIST)mutation detection
Publication Date：2010-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 269-272 )