Can left bundle branch pacing replace traditional biventricular pacing-CRT as the treatment for heart failure?
ZENG Jia-xin
ZOU Jian-gang
Abstract：Cardiac resynchronization therapy(CRT)is a important treatment for patients with chronic heart failure(HF)and electromechanical dyssynchrony.However,traditional biventricular pacing(BiVP)-CRT is associated with lead implantation failure and a considerable proportion of non-responders.Physiological pacing,mainly left bundle branch pacing(LBBP)has been rapidly developed in recent years.A series of studies have demonstrated that LBBP provides better left ventricular electromechanical resynchronization,cardiac function improvement and benefit in clinical outcomes compared to BiVP.Whether LBBP can replace traditional BiVP-CRT remains a key focus in clinical practice.In this article we aim to discuss this issue based on clinical studies,international and domestic guidelines,and expert consensus.
Keywords：left bundle branch pacingbiventricular pacingcardiac resynchronization therapyheart failure
Publication Date：2025-05-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 394-398 )