Perspectives on high-quality development of early screening,early diagnosis,and early treatment for colorectal cancer in China
ZHAO Ying-nan
GAO Jun-yan
HE Zi-xuan
BAI Yu
LI Zhao-shen
Abstract：The incidence and mortality rates of colorectal cancer in China have been increasing annually,with marked urban-rural and regional disparities.In recent years,important progress has been made in early colorectal cancer screening,leading to the preliminary establishment of a screening model suitable for the national context.This model centers on a"two-step"screening strategy,which involves initial screening through risk assessment questionnaires,fecal immunochemical testing(FIT),and fecal DNA testing,followed by colonoscopy for high-risk populations.However,current screening efforts still face challenges such as low public compliance,uneven distribution of endoscopic resources,and an incomplete screening system.With the rapid development of non-invasive screening technologies,including blood and fecal biomarker testing,the capability for early colorectal cancer screening and initial risk stratification has significantly improved.In the future,by integrating the advantages of colonoscopy with new non-invasive technologies and establishing dynamic risk assessment models and multi-dimensional screening systems,the efficiency of early screening will be further enhanced,and the rate of missed diagnoses will be reduced.This will provide crucial support for achieving high-quality development in the"early screening,early diagnosis,and early treatment"of colorectal cancer.
Keywords：colorectal cancerearly screeningcolonoscopybiomarkerrisk stratification
Publication Date：2025-05-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 373-380 )