Application of chimeric antigen receptor T cell therapy in autoimmune diseases
ZOU Bo
YANG Ping-ting
Abstract：Chimeric antigen receptor(CAR)T cell therapy is a type of immunotherapy that utilizes genetic engineering to modify a patient's T cells to express specific CARs,thereby enabling them to specifically recognize and eliminate tumor cells or target cells carryinging the target antigen.This therapeutic approach has shown encouraging results in autoimmune diseases such as systemic lupus erythematosus,antisynthetase syndrome,and pemphigus vulgaris;however,it also faces challenges in terms of safety,cost-effectiveness,and timing of treatment.
Keywords：chimeric antigen receptor T cellautoimmune diseasessystemic lupus erythematosus
Publication Date：2024-06-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 466-471,477 )