Characteristics of cognitive impairment in patients with metabolic syndrome
LI Qiang
SUN Fang
YAN Zhen-cheng
ZHU Zhi-ming
Abstract：Objective To explore the characteristics of cognitive impairment and the characteristics of EEG changes in patients with metabolic syndrome. Methods Totally 96 patients hospitalized between May 2017 and May 2018 were included in this study.Among them, there were 34 patients with type 2 diabetes, 20 patients with hypertension, and 42 patients with metabolic syndrome.All of them completed the physical examination, laboratory tests, assessment of cognitive function scale and the P300 test. Results There were significant differences in blood glucose, HBA1c, systolic blood pressure, BMI, waist circumference and triglyceride among the three groups (P<0.05). Compared with the patients with diabetes and hypertension, patients with metabolic syndrome had lower scores in digital memory tests, visual spatial ability, memory and total score in the memory and executive tests (P<0.05). Also the patients with metabolic syndrome had significant delayed P300 latencies than those with diabetes or hypertension (P<0.05), and decreased P300 amplitudes than diabetes group (P<0.05), but there was no significant difference compared with the hypertension group (P>0.05).Conclusion The cognitive impairment of patients with metabolic syndrome manifests itself in memory, execution, visual space, etc., and has its own damage characteristics.The event-related potential is characterized by prolonged information processing time of the prefrontal lobe and reduced processing capacity.
Keywords：metabolic syndromecognitive functionevent-related potentialP300
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 358-361 )