Current situation and evidence of glucocorticoid therapy for acute exacerbation of chronic obstructive pulmonary disease
SUN Wan-lu
CHEN Ya-hong
Abstract：Exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the management of COPD because they negatively impact health status, rates of hospitalization and readmission, and disease progression. However, currently, inappropriate and irrational use of glucocorticoids is quite common in the process of the treatment of acute exacerbation of COPD. For example, there are problems in the drug population, type, dosage form, dosage, drug delivery pathway, course of treatment, withdrawal, etc., which lead to a series of side effects. Proper use of glucocorticoids can improve lung function (FEV1), oxygenation and shorten recovery time. This article reviews the current use of glucocorticoid in treatment of AECOPD, outlines the recent global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease and the expert consensus of acute exacerbation, and explores the role of glucocorticoid in the treatment of AECOPD ibased on evidence-based medicine.
Keywords：chronic obstructive pulmonary diseaseacute exacerbationglucocorticoidtreatment status
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 446-450 )