Comparison of diagnostic accuracy between magnetically controlled capsule gastroscopy and conventional gastroscopy: a meta analysis and system review.
ZHU Jia-hui
CHEN Wen-xiao
RU Nan
QIAN Yang-yang
LIAO Zhuan
LI Zhao-shen
Abstract：Objective This study aims to evaluate the difference between Magnetically Controlled Capsule Gastroscopy and Traditional Gastroscopy in the detectability of gastric diseases, adverse events and examination time. Methods Articles related to the Magnetically Controlled Capsule Gastroscopy, published until November 2017, were retrievaled in the databases including PubMed, Cochrane library, Medline, VIP Chinese Science and Technology Periodical Database, China Knowledge Source Database (CNKI), Wanfang Data Resource Library and China Biomedical Literature Database.We evaluated articles based on QUADAS scale and extracted data including positive detection rate, examination time and adverse events. RevMan5.3 software and Meta-disc1.4 software were applied for data analysis, forest map and SROC curve presentation. Results After deleting duplicate articles and searching trials about MCCG and traditional gastroscopy, 9 studies with 626 patients were retained for analysis. Four studies were brought into detection rate analysis. The pooled sensitivity was 0.94 (95％CI: 0.9-0.97), pooled specificity was 0.73(95％CI: 0.51-0.89), positive likelihood ratio was 3.1(95％CI:1.65-5.38), negative likelihood ratio was 0.09(95％CI: 0.04～0.21)and the SROC area under the curve (AUG) was 0.9718,Q=0.9228. No statistical difference existed between Magnetically controlled Capsule Gastroscopy and Traditional Gastroscopy in detectability of gastric diseases. Inaddition, less patients reported adverse events, pain and discomfort during MCCG examination. However, the examination time of MCCG was significantly longer than that of conventional gastroscopy. Conclution Compared with conventional gastroscopy, Magnetically controlled Capsule Gastroscopy is a promising modality for gastric examination with comparable detability of gastric diseases and lower sdverse events.
Keywords：magnetically controlled capsule gastroscopytraditional gastroscopymeta analysissensitivity and specificityadverse reactionsexamination time
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 358-363 )