Systemic mastocytosis
WU Bin
WAN En-di
Abstract：Mastocytosis is a heterogeneous disease,systemic mastocytosis is defined by compact multifocal mast cell infiltrates in bone marrow or extracutaneous tissues and other minor SM criteria,with or without skin involvement.The diagnosis of SM is difficult for complicated by hematologic nonmast cell lineage disease.In the updated WHO classification 2016,a new category is proposed.Tyrosine kinase inhibitors,multikinase inhibitor and antibody-drug conjugate may have potential efficacy in the treatment.
Keywords：systemic mastocytosisKIT mutationmultikinase inhibitor
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 117-122 )