Analysis of the correlation of homocysteine with lipid profiles in health-examination people
HAO Qing-qing
ZHOU Zi-yi
WENG Hao-yu
LI Jian-ping
Abstract：Objective To investigate the correlation between homocysteine and lipid profiles in health examination people.Methods Based on data of 6013 subjects undergoing health examination in Peking University First Hospital,including height,weight,medical history,blood pressure,triglyceride,total cholesterol,low density lipoprotein,high density lipoprotein,homocysteine and other indicators,multiple linear regression model was used to analyze the relationship between homocysteine and lipid profiles.Results People with homocysteine ≥15 tμmol/L had higher age,body mass index,blood pressure,triglyceride,total cholesterol,low density lipoprotein,and lower levels of high density lipoprotein (P＜ 0.001).When continuous variables,with the increase of Hcy,high density lipoprotein decreased,while low density lipoprotein increased.Hcy was used as a grouping variable,subjects with medium level of Hcy had higher LDL and total cholesterol,and subjects with high level of Hcy had higher LDL and lower HDL.Conclution The increase of Hcy level is an independent risk factor for the increase of LDL and TCHO and the decrease of HDL.
Keywords：homocysteinetriglyceridetotal cholesterollow density lipoproteinhigh density lipoprotein
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 47-51 )