Risk factors of death in patients requiring day-time continuous renal replacement therapy for acute kidney injury after cardiac surgery
XU Tian-hua
WEI Min
SHAO Ming-lei
YAO Li
Abstract：Objective To study the risk factors of death and analyze the changes of the factors after day-time continuous renal replacement therapy(DCRRT) in AKI patients requiring DCRRT after cardiac surgery.Methods We reviewed the clinical data of the 42 AKI patients who received DCRRT after cardiac surgery in cardiovascular surgery of the First Affiliated Hospital of China Medical University,and divided them into two groups:survivors group(n=22)and non-survivors group(n=20).Univariate analysis and multivariable logistic regression were used to identify risk factors of death and we used paired t test to analyze the changes of the factors after DCRRT.Results Thefatality ratio of patients who required DCRRT after cardiac surgery was47.6％(20/42).There was statistical difference in the following factors between survivors and non-survivors:low cardiac output syndrome,age,the time of CPB,etc(P＜0.05).There was also statistical difference in the heart rate,mean arterial pressure,renal function and so on(P＜0.01).Multivariable logistic regression had identified the following factors as independent risk factors:mean arterial blood pressure and the density of bicarbonate in blood serum before DCRRT.Obvious improvements in homodynamic and renal function were found after D CRRT.Conclusion The renal function is improved and the homodynamic status is more stable after DCRRT.Mean arterial blood pressure and the density of bicarbonate in blood serum before DCRRT are the independent protective factors.
Keywords：renal replacement therapycardiac surgeryacute kidney injury
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 822-825 )